Scientific Programme - Full programme (by theme)
The Main Sessions of the congress will be supplemented by the extensive programme of Discussion Group Sessions, Teaching Sessions, Skills Workshops over 5 days as well as several special Symposia and a comprehensive schedule of free communications in the form of both oral and poster presentations.
Drug Therapy Basic Science Adult Epileptology Neuroimaging
Neurophysiology Paediatric Epileptology Psychiatric / Social Issues
Discussion
Group
Any progress in the treatment of epilepsy in pregnancy?
Tomson, Torbjörn (Sweden), Chair
Major
congenital malformations and AEDs: what have we learned from the
pregnancy registries?
Battino, Dina (Italy)
Prenatal
exposure to AEDs and long-term cognitive development: are there drug
specific adverse effects?
Eriksson, Kai (Finland)
Pregnancy
induced alterations in AED kinetics: how can dosage be optimised?
Johannessen, Svein I. (Norway)
Mechanisms of AED
developmental toxicity: state of the art and could pregnancy registries
be used to advance our understanding?
Finnell, Richard (USA)
Discussion
Group
Structure modifications to improve antiepileptic drugs
(AEDs) risk/benefit ratio
Johannessen,
Svein I. (Norway), Chair
Structure-activity
relationships (SAR) for AEDs
White, Steve (USA)
Strategies
for structure modifications: candidate compounds, rationale,
preparation and screening
Klitgaard, Henrik (Belgium)
Improving
pharmacokinetics and safety through structural modifications: lessons
from Valproic Acid derivatives
Bialer, Meir (Israel)
Structural AED analogues in clinical development: an overview
Perucca, Emilio (Italy)
Discussion
Group
Does prenatal exposure to carbamazepine or valproate
impair cognitive development?
Gaily,
Eija (Finland), Chair
Impact of
parental exposure to valproate and carbamazepine on cognition in animal
studies
Frisch, Christian (Germany)
Confounding
factors in humans: does maternal epilepsy per se affect cognitive
development in the offspring?
Eriksson, Kai (Finland)
Does
prenatal valproate exposure cause cognitive impairment?
Adab, Naghme (UK)
Is prenatal carbamazepine
exposure safe for cognitive development?
Gaily, Eija (Finland)
Teaching
Session
Treating epilepsy
Kasteleijn Nolst Trenite,
Dorothée (Netherlands), Chair
Diagnosis
and misdiagnosis
Genton, Pierre (France)
Starting
and stopping treatment
Gil Nagel, Antonio (Spain)
The place of polytherapy
Brodie, Martin (UK)
Teaching
Session
Pharmacogenomics: its place in the clinical management in
epilepsy
Sisodiya,
Sanjay (UK), Chair
Pharmacogenomics:
has it changed clinical practice in other fields?
Pirmohamed, Munir (UK)
Pharmacogenomics:
why consider it in epilepsy?
Delanty, Norman (Ireland)
Pharmacogenomics: how might it
integrate into patient management in epilepsy?
Baulac, Michel (France)
Teaching
Session
To treat or not to treat? – decisions under uncertainty
Sillanpää,
Matti (Finland), Chair
Drug
treatment after first seizure?
Trinka, Eugen (Austria)
Do we have
to treat all childhood epilepsy syndromes?
Bauer, Gerhard (Austria)
Drug
treatment in childhood status epilepticus – when do risks of treatment
outweigh the benefits?
Arzimanoglou, Alexis (France)
How urgent and aggressive should we treat non-convulsive
status epilepticus?
Shorvon, Simon (UK)
Discussion
Group
Analysis of brain function with antiepileptic drugs and
therapeutic monitoring
Stefan,
Hermann (Germany), Chair
Brain
function and AED in animals
Kubova, Hana (Czech Republic)
Mechanisms
of action detected by transcranial magnetic stimulation
Paulus, Walter (Germany)
Quantification
of epileptogenicity in humans
Stefan, Hermann (Germany)
Neuropsychological changes
during antiepileptic drug treatment
Aldenkamp, Albert P (Netherlands)
Discussion
Group
Can we replace the term “generalized” seizures?
Tinuper,
Paolo (Italy), Chair
Cortical
trigger in generalized seizures in rodents and humans
Lopes Da Silva, Fernando (Netherlands)
Brainstem
and forebrain networks in generalized seizures in rodents and humans
Mares, Pavel (Czech Republic)
Why some
antiepileptic drugs are effective on generalized seizures?
Schmidt, Dieter (Germany)
What are generalized seizures and epilepsies ?
Hirsch, Edouard (France)
Discussion
Group
Fast activity at seizure onset in human and animal
temporal lobe
Köhling,
Rüdiger (Germany) and Chauvel, Patrick (France) Chairs
Characterization
of fast discharge in various type of human partial epilepsies
Bartolomei, Fabrice (France)
Electrographic
patterns of seizure onset: can they tell us about the triggering
mechanisms?
Bragin, Anatol (USA)
Fast
network oscillations preceding seizures in rat hippocampus
Jeffreys, John G R (UK)
Network mechanisms of fast
activity at seizure onset in the entorhinal cortex
De Curtis, Marco (Italy)
Discussion
Group
From gene profiling to identification of new
antiepileptogenic targets
Aronica,
Eleonora (Netherlands), Chair
Gene
expression during epileptogenesis in the rat: on the search for
antiepileptogenic targets
Gorter, Jan (Netherlands)
From
profiling data to functional analysis of genes: focus on plasminogen
system
Pitkänen, Asla (Finland)
Human
temporal lobe epilepsy: from microarray to biological networks
Becker, Albert J (Germany)
Genomic
approaches to developmental disorders associated with epilepsy
Aronica, Eleonora (Netherlands)
Single-cell gene expression
analysis: implications for cortical malformations
Crino, Peter B. (USA)
Discussion
Group
Involvement of limbic seizure circuitry in absence
epilepsy
Onat,
Filiz (Turkey), Chair
Cerebral
glucose utilization of limbic structures in absence epilepsy models
Nehlig, Astrid (France)
Limbic
excitability in absence epilepsy models
Van Luijtelaar, Gilles (Netherlands)
Is limbic
seizure circuitry involved in absence epilepsy models?
Onat, Filiz (Turkey)
Co-existence of absence and temporal lobe epilepsies in humans
Ozkara, Cigdem (Turkey)
Discussion
Group
Pathophysiological role of GABAergic transmission in
epilepsy
Köhling,
Rüdiger (Germany), Chair
Tonic
GABAergic inhibition in epilepsy
Walker, Matthew (UK)
GABAergic
synchronization as a promoter of epileptiform activity
Avoli, Massimo (Canada)
Pathophysiological
role of chloride transporters in epilepsy
Kaila, Kai (Finland)
GABA and the initiation of
ictal activities in tissue from patients with temporal lobe epilepsies
Miles, Richard (France)
Discussion
Group
Search of biomarkers for epileptogenesis
Pitkänen,
Asla (Finland), Chair
Use of EEG
in search of biomarkers for epileptogenesis - review of animal data
Pavel, Mares (Czech Republic)
Use of EEG
in search of biomarkers for epileptogenesis - review of human data
Halasz, Peter (Hungary)
Hypes and
hopes for MR/SPECT/PET imaging as a sensor for epileptogenesis
Nehlig, Astrid (France)
CSF as a
candidate source for biomarker identification
Kurkinen, Kaisa (Finland)
Assessment of cognitive
function - does it reveal the patients at risk?
Helmstaedter, Christian (Germany)
Discussion
Group
The role of parahippocampal brain areas in temporal lobe
epilepsy
Sperk,
Guenther (Austria), Chair
Morphological
and neurochemical plasticity of parahippocampal areas in the kainate
model of TLE
Sperk, Guenther (Austria)
Metaplasticity
at CA1-subiculum synapses in temporal lobe epilepsy
Behr, Joachim (Germany)
Acute
ictal discharges in the entorhinal-perhirinal cortices
De Curtis, Marco (Italy)
Threshold behavior in the initiation of hippocampal population
bursts
De La Prida, Liset Mendelez (Spain)
Workshop
Session
Sodium channel defects in genetics and pharmacogenetics
of epilepsy
Lerche,
Holger (Germany), Chair
SCN1A and
SCN2A mutations in epilepsy
De Jonghe, Peter (Belgium)
Lessons
from SCN1A knock-out mice
Mantegazza, Massimo (Italy)
Potential
role of a neonatal SCN1A splice variant in drug response
Schorge, Stephanie (UK)
Correlation of drug response
to Na channel blockers in vivo and in vitro
Beck, Heinz (Germany)
Workshop
Gap-junctions and epilepsy
Spreafico,
Roberto (Italy), Chair
Gap -
junctions and connexins expression in the CNS
Condorelli, Daniele (Italy)
Gap
junctional communication in astrocytes and neuroglial interaction
Giaume, Christian (France)
Physiology
of gap-junctions
Heinemann, Uwe (Germany)
Antiepileptic effect of gap-junctions blockers
Cock, Hannah (UK)
Workshop
Role of aquaporin water channels in pathophysiology of
epilepsy
Nagelhus,
Erlend (Norway), Chair
Anatomy
and physiology of aquaporins
Nagelhus, Erlend (Norway)
Aquaporins,
water balance and epilepsy - studies in animal models
Binder, Devin K. (USA)
Aquaporins and temporal lobe
epilepsy – genetic aspects
Heuser, Kjell (Norway)
Neurobiology
Symposium
Neuro-glia signaling and epilepsy
Steinhauser, Christian (Germany), TBA, Chairs
Astrocytes in the epileptic brain: role in seizure generation
and neurovascular coupling in experimental models
Carmignoto, Giorgio (Italy)
Glia-neuronal signaling during neocortical
epileptogenesis
Friedman, Alon (Israel)
Astrocyte-neuron communication in human brain tissue
Perea,
Gertrudis (Spain)
A role for astrocyte dysfunction in human epilepsy
Steinhauser, Christian (Germany)
Discussion
Group:
Meet the
Editors
Pitkanen,
Asla (Finland), Schaechter, Steven (USA), Shorvon, Simon (UK)
Discussion
Group
Lesion versus epilepsy driven hemisphere dominance in epilepsy?
Helmstaedter, Christian (Germany), Chair
Language dominance related to epileptiform activity
Woermann, Friedrich (Germany)
Language fMRI and tractography pre- and post-surgery:
evidence for structural and functional plasticity
Bonneli, Silvia (UK)
Stability
of language dominance patterns from before to after
surgery
Alpherts, Willem (The Netherlands)
Postoperative
reshift of
right
into left hemisphere language dominance
Fritz, Navah (Germany)
Discussion
Group
Neuromodulation and epilepsy, how to match basic research
and clinical practice?
Ben Menachem, Elinor (Sweden), Chair
Neurogenesis
in epilepsy, what is the evidence?
Kuhn,
Georges (UK)
Neuromodulation
in epilepsy,
what is the evidence?
Wadman, Wytse J. (Netherlans)
Neuromodulatory treatments
in
clinical practice, what is the
evidence?
Vonck, Kristl (Belgium)
Neuromodulatory treatments in
the future, what can we expect?
Boon, Paul (Belgium)
Discussion
Group
The nosology of the epilepsies: what is “idiopathic generalized
epilepsy”?
Janz, Dieter (Germany), Chair
Molecular genetics of IGE
Zara, Federico (Italy)
PET
and SPECT findings in IGE
Koepp, Matthias (UK)
MR imaging and spectroscopy
in
IGE
Woermann, Friedrich (Germany)
Reflex
epileptic traits in IGE
Wolf, Peter (Denmark)
Discussion
Group
The ominous effects of epilepsy- avoiding, evading and preventing them
Neufeld, Miri (Israel), Chair
Seizure related traumas and
injuries
Neufeld, Miri (Israel)
Status
epilepticus
Shorvon, Simon (UK)
Sudden unexpected death in
epilepsy
Tomson, Torbjörn (Sweden)
Depression
and suicide in
epilepsy
Elliot, Brent (UK)
Discussion
Group
Understanding dissociative (non epileptic) seizures: mechanisms and
presentations
Goldstein, Laura (UK), Chair
Predisposing, precipitating and
perpetuating factors: an
overview
Reuber, Markus (Germany)
Phenomenological
aspects of
dissociative seizures: clues to
mechanisms
Mellers, John D. C. (UK)
Stress physiology and
emotional
processing in dissociative
(non-epileptic) seizures
Roelofs, Karin (Netherlands)
The subjective side of
dissociative (non-epileptic) seizures
and their psychodynamics: conversational patterns between patients and
doctors
Schondienst, Martin (Germany)
Teaching
Session
Adult patients with epileptic encephalopathies of
childhood
Genton, Pierre (France), Chair
Dravet syndrome beyond
childhood
Dravet, Charlotte (France)
The
Lennox-Gastaut syndrome
patient as an adult
Nikanorova, Marina (Denmark)
The
Rasmussen syndrome: a
long-term perspective
Bien, Christian (Germany)
Teaching
Session
Limbic circuitry, emotions and epilepsy. structures involved,
clinical picture and therapeutic possibilities
Martins Da Silva, Antonio (Portugal), Chair
Limbic structures, emotions
and
epilepsy
Lopes Da Silva, Fernando (Netherlands)
Semiology and cognitive
assessment of seizures with intense
emotional component
Meletti, Stefano (Italy)
Functional
and structural
approach to emotional and autonomic
components in epileptic seizures
Bartolomei, Fabrice (France)
Influence
of epilepsy surgery
on emotions and autonomic components of limbic seizures in non-operated
patients
Wellmer, Jorg (Germany)
Teaching
Session
Nonconvulsive status: specific features and specific etiologies
Thomas, Pierre (France), Chair
Nonconvulsive status in the
ring chromosome 20 syndrome
Zuberi, Sameer (UK)
Nonconvulsive status triggered
by anticonvulsants
Thomas, Pierre (France)
Nonconvulsive
status in the
elderly:diagnostic problems and
therapeutic issues
Fernandez Torre, Jose Luis (Spain)
Teaching
Session
Status epilepticus: from basic science to prognosis
Rossetti, Andrea (Switzerland), Chair
Epidemiology
of status
epilepticus
Logroscino, Giancarlo (USA)
Pathophysiology of status
epilepticus
Holtkamp, Martin (Germany)
Treatment
of status
epilepticus
Rossetti, Andrea (Switzerland)
Workshop
EPICURE: EU funded research into functional genomics and neurobiology
of epilepsy, a basis for new therapeutic strategies
Avanzini, Giuliano (Italy), Chair
The genetics of human
epilepsies
Sander, Thomas (Germany)
Functional
analysis of ion
channel mutations in genetic
epilepsies and pharmacoresistance
Lerche, Holger (Germany)
Acquired channelopathies and
loss of control excitation
Walker, Matthew (UK)
Pharmacogenetics
of refractory
epilepsy
Perucca, Emilio (Italy)
Workshop
Hypermotor seizures : from definition to underlying
networks
Nobili, Lino (Italy), Chair
Hypermotor seizures: are they
always clinically the same?
Noachtar, Soheyl (Germany)
Do
hypermotor seizures always
originate from the frontal lobe?
Kahane, Philippe (France)
Hypermotor seizures and
sleep:
what is the link?
Picard, Fabienne (Switzerland)
Hypermotor seizures: a release
phenomenon of inborn
behaviours?
Tassinari, Carlo Alberto (Italy)
Workshop
Relevance of interictal discharges in epilepsy
Pressler, Ronit (UK), Chair
Pathophysiology of interictal
discharge
Avoli, Massimo (Italy)
Effects
of epileptiform
discharges on the immature brain
Ben-Ari, Yezekiel (France)
Effect of interictal
discharges
on cognition and behaviour
Pressler, Ronit (UK)
Relevance
of nocturnal
discharges
Deonna, Thierry (Switzerland)
Workshop
Seizure or parasomnia? the limits of expertise
De Weerd, A. W. (Netherlands), Chair
This is epilepsy! Or is it?
Van Emde Boas, Walter (Netherlands)
This
is sleep! Or is it?
(Adults)
Kelemen, Anna (Hungary)
This is sleep! Or
is
it? (Children)
De Weerd, A. W. (Netherlands)
Intracranial studies: nearer to
the source, not always to the
solution
Nobili, Lino (Italy)
Workshop
How
to get the most of your imaging – a workshop.
Ryvlin, Philippe (France), Chair
Making the most of your MRI
Huppertz, Hans-Jürgen (Switzerland)
Pitfalls in PET imaging
Hammers, Alexander (France)
SPECT
Dupont, Patrick (Belgium)
Pitfalls
in fMRI imaging
Koepp, Matthias (UK)
Discussion
Group
Simultaneous EEG-fMRI recordings in epilepsy: state of the art and
critical review
Siniatchkin, Michael (Germany), Lemieux, Louis
(UK), Co chairs
EEG-fMRI
in epilepsy: a
critical view on methodology
Benar, Christian (France)
EEG-fMRI studies in
generalized epilepsies
Laufs, Helmut (Germany)
EEG-fMRI studies in focal
epilepsies
Thornton, Rachel (UK)
Special
aspects of EEG-fMRI:
influence of age, vigilance and
type of epileptiform discharges
Siniatchkin, Michael (Germany)
Teaching
Session
Pitfalls in waking and sleep EEG diagnosis
Crespel, Arielle (France), Chair
Unusual
EEG activities in wakefulness and sleep
Gelisse, Philippe (France)
Pitfalls
in activation procedures
Kasteleijn Nolst Trenite, Dorothée (Netherlands)
Particularities
of deep EEG recordings vs scalp EEG
Wieser, Heinz Gregor (Switzerland)
Discussion
Group
“Practical” epileptogenic zone : non invasive definition
in children
Chrion, Catherine (France), Chair
Usefulness and limits of clinical phenomenology?
Tassi, Laura (Italy)
Scalp EEG:
truths and pitfalls?
Hirsh, Edouard (France)
When
to believe in morphological brain imaging?
Harkness,
William (UK)
Functional
brain
imaging: to
perform or not?
Chiron, Catherine (France)
Discussion
Group
Focal cortical dysplasia type I: are there
electro-clinical and seizure outcome differences between children and
adults?
Komárek, Vladimír (Czech Republic), Chair
Neuropathological characteristics of different types of focal cortical dysplasia Blümcke, Ingmar (Germany)
Focal
cortical
dysplasia type I in adults
Tassi, Laura (Italy)
Focal
cortical dysplasia type I in children
Krsek, Pavel (Czech Republic)
'Mild'
cortical
dysplasia - severe epilepsy
(summary and
opening the discussion)
Holthausen, Hans (Germany)
Discussion
Group
How many immunomediated epileptic encephalopathies exist in children?
Vigevano, Federico (Italy), Chair
Overview
of clinical entities
Fusco, Lucia (Italy)
Immunological
markers
Vincent, Angela C (UK)
Devastating
epileptic encephalopathies
Dulac, Olivier (France)
Therapeutic
prospectives
Bien, Christian G. (Germany)
Teaching
Session
Childhood absence seizures, epilepsies, syndromes
Covanis, Athanasios (Greece), Chair
Pathophysiology
of human absence epilepsy
Moshe, Solomon (USA)
Clinical
variability of absence seizures/syndromes
in
childhood and adolescence
Covanis, Athanasios
(Greece)
Genetics
of
absence seizures
Pinto, Dalila (Netherlands)
Teaching
Session
Deficient energy metabolism presenting as epileptic seizures or status
epilepticus
Pihko, Helen (Finland), Chair
The
role of
mitochondria in epileptogenesis
Pihko, Helen (Finland)
Epileptic
encephalopathy in children with Twinkle -
mutations
Lonnqvist, Tuula (Finland)
Impaired
glucose
transport
into the brain
Klepper, Jörg (Germany)
Workshop
Treating epileptic encephalopathies: state of the art
Ben-Zeev Ghidoni, Bruria (Israel), Chair
Aggressive
treatment for devastating disease
Kramer, Uri (Israel)
Useful,
useless
or dangerous AEDs
Arzimanoglou, Alexis (France)
Are
IV
immunoglobulines useful: when, how, for how
long?
Lagae, Lieven (Belgium)
Surgery:
can it
only be palliative?
Cross, Helen (UK)
Discussion
Group
Crime and punishment: legal aspects of epilepsy and AED treatment
Trimble, Michael (UK) and Schmitz, Bettina (Germany), Chairs
Epilepsy
and motherhood. What are the
dangers of mothers with
epilepsy injuring their children?
Crawford,
Pamela (UK)
Unforeseen
Side effects of antiepileptic
drugs
Schwabe, Stefan (USA)
Assessment
of mental capacity in people with
epilepsy
Trimble, Michael (UK)
Epilepsy
and driving - the
European perspective
Beghi, Ettore (Italy)
Wokshop
The effects of epilepsy and its treatment on cognitive
functioning: immediate and long-term
Baker, Steven Kemp (UK)
Natural
history of cognitive impairment in
children with
epilepsy
Aldenkamp, Albert P (Netherlands)
Immediate
impact of epilepsy and its
treatment in adults
Taylor, Joanne (UK)
The
long term
outcome of epilepsy and its treatment on neuropsychological function
Steven Kemp
(UK)
The
theoretical underpinnings of neuropsychological functioning in people
with epilepsy
Kälviäinen, Reetta (Finland)
Workshop
Genetically determined epilepsy syndromes associated with
intellectual disability
Huber, Bernd (Germany), Chair
Molecular
genetic associations between intellectual disability
and epilepsy
Daniella Pilz (UK)
Idiopathic'
genetic epilepsy phenotypes associated with severe
learning disability or Channelopathies associated with epilepsy and
severe learning disability
Nabout, Rima (France)
Epilepsy
and autonomic disturbance in Rett syndrome
Kerr,
Mike (UK)
The
epilepsy phenotypes of Angelman's and Fragile X syndrome
Elia, Maurizio (Italy)
